Platelet Activation

START 5 Platelet Activation

1. Biological Effect: Hemocompatibility Tests 
2. Turnaround time: 6 weeks
3. Sample Requirements:


30 cm² (test item < 0.5 mm thick);
18 cm² (test item ≥ 0.5 mm thick);
1 gram;
5 ml;
at least 3 test items;


ISO 10993-4

Activated platelets are pro-thrombogenic. Platelet activation can be evaluated by various means, such as microscopic (light and electron microscopy) examination of morphology of platelets adherent to the medical device and measurement of βTG, PF4 and TxB2 released from activated platelets and can be assessed by an ELISA. Increases in platelet activation can occur through multiple paths associated with medical devices.