PYROGENICITY in EBI

PYROGENICITY is the ability of a chemical agent or other substance to produce a febrile response.
Pyrogenic responses may be material-mediated, endotoxin-mediated, or mediated by other substances.
In accordance with the ISO 10993-11 we commonly conduct two test types:
LAL (Limus Amebocyte Lisate) test to detected endotoxin-specific factors,
Material-mediated pyrogenicity test (Rabbit Pyrogen Test) which has a wide range for detecting non-endotoxin pyrogenicity for example endogenous pyrogens, prostaglandins, bacterial exotoxins, neurotransmitters and metals such as nickel salt, in same instances.
Are you confused what kind of test you need.
Contact us to choose the right method for your device!

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